第 4 季 共 16 集
播出时间：2009年10月19日
第 1 集 Blood of the Father, Heart of Steel
播出时间：2009年10月19日
Henchman 21 copes with life without 24. Brock and the Venture family are forced to part ways. Discover the final fate of H.E.L.P.eR. And Dean must kill Hitler.
第 2 集 Handsome Ransom
播出时间：2009年10月26日
The Monarch decides to settle for cash as the best revenge on Dr. Venture and takes Hank and Dean hostage. However, Hank is rescued by Captain Sunshine, who wants a new boy sidekick to replace his fallen comrade Wonder Boy.
第 3 集 Perchance to Dean
播出时间：2009年11月2日
Rusty begins to indoctrinate Dean into his career as a super scientist, not knowing that a deformed and believed aborted Dean clone stalks the compound. The deformed clone's attempt to kill Dean leads to a mix up with Hank thinking that he's killed his brother, while local police prepare to raid the Compound after a UPS delivery man suspects illegal activities going on.
第 4 集 Return to Malice
播出时间：2009年11月9日
Henchman 21 kidnaps the Venture brothers without The Monarch's knowledge or consent, resulting in Sgt. Hatred having to storm his former hometown of Malice to rescue his charges. We also learn of the recent activities of 21 since the death of 24.
第 5 集 The Revenge Society
播出时间：2009年11月16日
The Guild of Calamitous Intent comes under attack by an insane Phantom Limb, who now goes by the name "Revenge". Meanwhile, Hank and Sergeant Hatred must protect the compound from the Guild's agents. We also learn something very interesting about Dean's birthright.
第 6 集 Self-Medication
播出时间：2009年11月23日
While Dr. Venture goes into therapy with other boy adventurers, Sgt. Hatred takes Dean and Hank to the movies, only to have a relapse.
第 7 集 The Better Man
播出时间：2009年12月7日
After seeing the OutRider, the man who stole his wife, pass through the Second World, Dr. Orpheus is determined to do the same. Meanwhile, Hank takes Dean to the mall to teach him how to talk to girls, and Triana has a life-altering discussion with The Master.
第 8 集 Pinstripes & Poltergeists
播出时间：2009年12月14日
While the Monarch schemes to dispose of Dr. Venture once and for all, Henchman 21 seeks revenge on Brock for the death of 24.
第 9 集 The Diving Bell vs. The Butterglider
播出时间：2010年9月13日
Brock, Hank, and Dean must go on a fantastic voyage into Rusty's brain to find out why he's in a coma. Meanwhile, Henchman 21 demands new henchsuits, but the Monarch is too busy obsessing with his latest purchase, a butter-glider.
第 10 集 Pomp & Circuitry
播出时间：2010年9月20日
Hank and Dean graduate from their education beds, and look into college. Hank rebels and tries to join Sphinx. Meanwhile, Phantom Limb breaks out of the Guild's dungeons and seeks revenge once more.
第 11 集 Any Which Way But Zeus
播出时间：2010年9月27日
Someone is capturing heroes and villains and taking them to a super death camp. The forces of good and evil must join forces to stop their mysterious captor.
第 12 集 Everybody Comes to Hank's
播出时间：2010年10月4日
Hank opens a detective agency and enters a dark world of sinister crime and shady women.
第 13 集 Bright Lights, Dean City
播出时间：2010年10月11日
Dean ends up interning with Professor Impossible, and discovers that his new employer is a member of the Revenge Society.
第 14 集 Assisted Suicide
播出时间：2010年10月18日
Dr. Venture is possessed by an entity that attempts to make him commit suicide, and Dr. Orpheus tries to save him.
第 15 集 The Silent Partners
播出时间：2010年10月25日
Conjectural Technologies' newfound success hits a snag when Billy is kidnapped by the same mysterious benefactors who invested in their company, and SPHINX launches an investigation aimed at determining who is behind these dubious financiers.
第 16 集 Operation: P.R.O.M.
播出时间：2010年11月22日
Team Venture, Conjectural Technologies and the Order of the Triad come together as Dean and Hank prepare to face an obstacle that is more intimidating then anything they have confronted before: a prom to celebrate their "graduating" high school, while Dr. Venture throws out all the stops to bring the twins the best dance $500 can buy. But when things go awry, the greatest battle in Venture history looms as two old enemies - the OSI and SPHINX - clash once again.
