第 5 季 共 18 集
播出时间：2017年3月13日
第 1 集 Dr. Dustiny
播出时间：2017年3月13日
While searching for Charlie, Alex finds a caterer who was caught in the crossfire. Grace's mother asks for a priest. Dana consults with Cassie about a male stripper.
第 2 集 Midlife Crisis
播出时间：2017年3月20日
Alex and Charlie are confused about their relationship. Alex and Maggie disagree about a car crash survivor. Dana is forced to treat an injured motorcyclist. Zach bothers Maggie about dating.
第 3 集 Birthday Blues
播出时间：2017年3月27日
Alex makes a promise to a young girl on her birthday. Maggie organizes a surprise party for Alex. Cassie is forced to confront her fear of infectious diseases.
第 4 集 A Stranger Comes to Town
播出时间：2017年4月3日
Charlie tries to save the arm of a man thrown from a horse. Alex joins Manny off-site to help a runaway. A rival from Dev's past arrives at Hope Zion.
第 5 集 Tested and Tried
播出时间：2017年4月10日
Alex tracks down the father of a patient who needs a liver transplant. The new CEO of Hope Zion is at odds with Dawn. Zach faces trials in the E.R.
第 6 集 Doctor Robot
播出时间：2017年4月17日
Alex and Maggie ask Charlie for his opinion on a patient's treatment. Zach is persuaded by a patient while transitioning the ER to an urgent care facility.
第 7 集 Gutted
播出时间：2017年4月24日
Alex and Maggie deal with a tough lawyer after surgical complications with their cancer study patient. With the E.R. now an urgent care facility, Zach and his team aren't equipped to handle an accident victim.
第 8 集 Knowing Me, Knowing You
播出时间：2017年5月1日
Charlie and Manny treat a couple. Maggie evaluates the interns. Billy asks Maggie to be his mentor. Dawn tries to get her Chief of Surgery position back.
第 9 集 All Our Yesterdays
播出时间：2017年5月8日
The doctors rally together to try to save an unknown man who was struck by a subway train. Randal delivers a warning about Charlie's gift. Dr. Sydney Katz returns to town.
第 10 集 Change of Heart
播出时间：2017年6月9日
Alex tries to distract herself from her grief. Charlie and Shahir try to track down Alex's brother. Alex treats a young girl with kidney failure. Maggie and Sydney treat a young woman with an STI.
第 11 集 Nightmares & Dreamscapes
播出时间：2017年6月16日
While Charlie tries to save a young man's life, he is haunted by a mischievous spirit.
第 12 集 Leap of Faith
播出时间：2017年6月23日
Alex and Maggie work together to deliver a baby. Charlie treats a magician.
第 13 集 Problem Child
播出时间：2017年6月30日
Alex tries to help patient who hurt himself breaking into a house. A friend of Dr. Dev Sekara has been beaten by the police; a heart patient wishes to open an animal sanctuary.
第 14 集 We Need to Talk About Charlie Harris
播出时间：2017年7月7日
Alex is challenged about the value of holistic medicine. Charlie's abilities are questioned. Two filmmakers go to Hope Zion Hospital.
第 15 集 Fix You
播出时间：2017年7月14日
The board questions the hospital staff about Charlie's behaviour. A patient convinces Alex to use new-age techniques. Shahir agrees to do an in-utero surgery.
第 16 集 La famiglia
播出时间：2017年7月21日
Alex has to put her concerns for Charlie aside when a chance to perform a cancer surgery arises.
第 17 集 First and Last
播出时间：2017年7月28日
Alex and Charlie put their wedding plans aside. Zach takes a special interest in a case. A coma patient who wakes up with no memory.
第 18 集 Hope Never Dies
播出时间：2017年8月4日
Alex and Charlie rush to the scene of a mass casualty accident involving a bus full of teenagers.
