第 5 季 共 20 集
播出时间：2019年9月26日
第 1 集 Never Going Back to Normal
播出时间：2019年9月26日
Will and Natalie battle for their lives after a car accident. An investigation is launched following the suspicious death of Cornelius Rhodes. Maggie receives life-changing news. Dr. Charles cuts his honeymoon short to tend to a patient.
第 2 集 We're Lost in the Dark
播出时间：2019年10月3日
Dr. Choi and Dr. Charles have difficult decisions to make as a dying man tries to preserve his future life with a controversial scientific method. Dr. Marcel and April clash over how to handle a mysterious patient and Will questions Natalie's capabilities. Sharon assigns a nurse to shadow Maggie, much to her dismay.
第 3 集 In the Valley of the Shadows
播出时间：2019年10月10日
Dr. Choi and Dr. Marcel don't see eye to eye over the treatment of a patient's chronic pain. Rumors circulate about Maggie. Dr. Manning works to help a young boy, but she is challenged by his parents, who believe in only using holistic remedies.
第 4 集 Infection, Part II (II)
播出时间：2019年10月17日
Dr. Manning's actions with a recent patient lead to serious repercussions. April and Noah disagree over a patient who is injured after a beating. Dr. Charles is visited by a childhood friend with a surprising revelation.<br />
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The crossover starts on Chicago Fire S08E04 Infection (I). It continues on Chicago PD S07E04 Infection, Part III (III).
第 5 集 Got a Friend in Me
播出时间：2019年10月24日
Dr. Choi and Dr. Marcel don't see eye-to-eye over the treatment of a patient's chronic pain and rumors start to circulate about Maggie. Dr. Manning works to help a young boy, but her treatment suggestions are challenged by the parents who believe in only using holistic remedies.
第 6 集 It's All in the Family
播出时间：2019年10月31日
Dr. Manning's actions with a recent patient lead to serious repercussions. April and Noah disagree over a patient who is injured after a beating. Dr. Charles is visited by a childhood friend with a surprising revelation.
第 7 集 Who Knows What Tomorrow Brings
播出时间：2019年11月7日
Dr. Charles and Dr. Halstead sink their teeth into a bloodthirsty case. Dr. Marcel and Maggie throw a traditional crawfish boil for the staff. A new relationship blossoms while another is left on rocky ground.
第 8 集 Too Close to the Sun
播出时间：2019年11月14日
Maggie gets unsettling news about a new friend and breaks protocol to support him. One of the doctors from the Med family is rushed into emergency surgery after a violent assault. A social media influencer lets his users vote on medical advice, forcing Dr. Charles to make a decision.
第 9 集 I Can't Imagine the Future
播出时间：2019年11月21日
April receives unfortunate news that makes her question her future with Ethan. Dr. Charles and Maggie see tough times on the horizon. Natalie’s memory from the accident starts to return.
第 10 集 Guess It Doesn't Matter Anymore
播出时间：2020年1月9日
Dr. Halstead's world is thrown into turmoil when a former patient resurfaces. April has a secret she considers confessing to Ethan. Dr. Charles tries to maintain his focus during a difficult time.
第 11 集 The Ground Shifts Beneath Us
播出时间：2020年1月16日
After a major accident at O'Hare, the E.D. is concerned one of their own is in mortal danger. Will's proposal for a safe injection site goes to the board for consideration. Natalie and Goodwin become concerned for Gwen.
第 12 集 Leave the Choice to Solomon
播出时间：2020年1月23日
The team deals with the aftermath of a school bus crash. Dr. Charles worries Dr. Halstead is putting his medical license in jeopardy. Maggie helps a friend in need.
第 13 集 Pain Is for the Living
播出时间：2020年2月6日
Two brothers in critical condition are rushed into the hospital by their parents, leaving Dr. Choi, April and Dr. Charles to tend to their care and left to piece together what actually transpired. Dr. Manning becomes suspicious of a new mother entering the E.D. Dr. Halstead’s tireless activities at the safe injection site start to take a toll on his work.
第 14 集 It May Not Be Forever
播出时间：2020年2月13日
Dr. Manning and Dr. Marcel disagree over an abusive husband. Dr. Halstead struggles with ethics and his decision to work at the safe injection site. Dr. Charles and Elsa reveal a misdiagnosis that may change a family’s life.
第 15 集 I Will Do No Harm
播出时间：2020年2月27日
Dr. Charles and Dr. Manning treat a patient who is fully invested in pretending to be someone other than himself. Noah begins to doubt his abilities as a doctor. Dr. Marcel and Dr. Choi are faced with a tough ethical decision. Dr. Halstead puts his faith in an addict.
第 16 集 Who Should Be the Judge
播出时间：2020年3月5日
A convicted murderer’s escape hits close to home when several members of the team find themselves in danger. Dr. Charles and Dr. Halstead continue to clash over patient treatment plans. Dr. Choi and April discover the truth about a patient’s scam. Maggie finally receives some good news.
第 17 集 The Ghosts of the Past
播出时间：2020年3月19日
Dr. Manning and Dr. Charles assist in a complicated case helping a 4-year old who they quickly learn is no stranger to the ED. Dr. Marcel and Dr. Choi tend to a police officer with a mysterious gunshot wound to the abdomen. Relationships are put to the test as secrets are revealed.
第 18 集 In the Name of Love
播出时间：2020年3月26日
Dr. Charles and Goodwin fear Dr. Halstead is repeating his past mistakes when a patient with early-onset Alzheimer’s is brought into the E.D. Maggie and Ben become concerned when one of Ben’s students is admitted. Dr. Manning and Dr. Marcel treat a terminally ill patient and disagree over the best course of action.
第 19 集 Just a River in Egypt
播出时间：2020年4月9日
Dr. Charles evaluates a 15-year old who is brought into the E.D. after an apparent fall off an overpass. Will sides with Dr. Asher on a risky treatment plan. Tensions run high between Dr. Choi and Dr. Marcel.
第 20 集 A Needle in the Heart
播出时间：2020年4月16日
Dr. Crockett is visited by two New Orleans detectives who have questions about his past. Dr. Choi puts his life in danger to save a child. Dr. Charles gives fatherly advice to his young daughter.
