第 5 季 共 26 集
播出时间：1988年10月7日
第 1 集 Together Again and Again
播出时间：1988年10月7日
As Theo begins his freshman year at New York University, Denise announces that she is dropping out of Hillman College. Sondra is revealed to be pregnant.<br />
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First mention of Cliff's theory that the children keep returning home because "they want the house."
第 2 集 The Physical
播出时间：1988年10月14日
Cliff prepares for a physical. John Amos as Dr. Bradley Herbert, Jr.
第 3 集 Rudy's All-Nighter
播出时间：1988年10月21日
Rudy's friend sleeps over.
第 4 集 Move It (a.k.a. The Baby Game)
播出时间：1988年10月28日
Everyone wants pregnant Sondra and Elvin to find a new house. Elvin's surname, Tibideaux, is revealed.
第 5 集 Out of Brooklyn
播出时间：1988年11月4日
Denise leaves Brooklyn for a job in Africa (Lisa Bonet's last appearance of Season 5).
第 6 集 The Birth (1)
播出时间：1988年11月11日
Sondra goes into labor, and Elvin is a nervous wreck.<br />
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Deon Richmond as Kenny. Michelle Thomas as Justine. First appearances of Reno Wilson as Howard, and Elizabeth Narvaez as Kara. Guest appearance by Naomi Campbell.
第 7 集 The Birth (2)
播出时间：1988年11月11日
Sondra gives birth to twins—a boy and a girl—who are named after Nelson Mandela and his then-wife Winnie. Elvin decides to return to medical school.
第 8 集 Cyranoise de Bergington
播出时间：1988年11月18日
Theo wants to date his friend Howard's ex-girlfriend, but he is stunned upon learning who she wants to date. Troy Winbush as Denny. Reno Wilson as Howard.
第 9 集 How Do You Get to Carnegie Hall?
播出时间：1988年12月2日
Vanessa, Janet and Kara want to be professional singers; Russell wins a prize in a sweepstakes, which turns out to be a toaster. Pam Potillo as Janet. Elizabeth Narvaez as Kara. Guest appearance by singer Betty Carter.
第 10 集 If the Dress Fits, Wear It
播出时间：1988年12月9日
Clair secretly goes on a crash diet and exercise program to lose five pounds in a week so she can fit into a dress. Appearance by Debbie Allen; voice-over by Ahmad Rashād (Phylicia Rashād's sister and husband).
第 11 集 Is There a Hamster in the House?
播出时间：1988年12月16日
Rudy takes care of a friend's hamster for the weekend.
第 12 集 Truth or Consequences
播出时间：1989年1月6日
Rudy lies to cover for Vanessa, who secretly goes out on a date with her older boyfriend.
第 13 集 Cliff Babysits
播出时间：1989年1月13日
Cliff babysits Winnie and Nelson when the rest of the family goes to see a Michael Jackson concert.
第 14 集 Mrs. Huxtable Goes to Kindergarten
播出时间：1989年1月27日
Clair appears as a panelist on a local Sunday morning talk show entitled "Retrospective". Clair buys a new couch and Cliff tries to keep the old one. Clair's law firm is identified as Greentree, Bradley & Dexter.
第 15 集 The Lost Weekend
播出时间：1989年2月3日
With the rest of the family gone for the night, Theo throws a "small" party that gets out of control. Troy Winbush as Denny. Reno Wilson as Howard. First appearance of Alex Ruiz as Lou. Cameo appearance by Joie Lee.<br />
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Phylicia Rashād (Clair), Malcolm-Jamal Warner (Theo), Tempestt Bledsoe (Vanessa), and Elizabeth Narvaez (Kara) appear on the episode of A Different World which airs later that evening.
第 16 集 No Way, Baby
播出时间：1989年2月7日
Cliff tracks down the grandfather of one of his patients: an expectant teenage mother with no other family. Clair deduces that the charming man is illiterate. Guest appearance by Sammy Davis, Jr.
第 17 集 Can I Say Something, Please?
播出时间：1989年2月10日
Rudy wants to change some of her rules. Voice-over by Ed McMahon (from The Tonight Show Starring Johnny Carson).
第 18 集 The Dead End Kids Meet Dr. Lotus
播出时间：1989年2月17日
Theo consults a voodoo shopkeeper for advice on winning his girlfriend back.<br />
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Troy Winbush as Denny. Reno Wilson as Howard. Alex Ruiz as Lou. Michelle Thomas as Justine. Guest appearances by Moses Gunn and Harold Perrineau.
第 19 集 The Boys of Winter
播出时间：1989年2月24日
Cliff's old basketball friend comes to visit. Guest appearance by U.S. Senator (and former NBA basketball player) Bill Bradley.
第 20 集 It Comes and It Goes
播出时间：1989年3月10日
Sondra bemoans taking care of the twins.
第 21 集 Theo's Women
播出时间：1989年3月17日
After catching Theo kissing another woman in the lounge of her dormitory, Justine breaks up with him. Desperate to win her back, Theo turns to Cliff for advice. Michelle Thomas as Justine. First appearance of Vanessa A. Williams as Jade.
第 22 集 Birthday Blues
播出时间：1989年3月31日
Clair's 46th birthday.
第 23 集 A Room With No View
播出时间：1989年4月14日
Vanessa and Rudy argue and fight. After the sisters do physical damage to the house, Cliff exiles them to the basement.
第 24 集 What He Did for Love
播出时间：1989年4月28日
Theo's friend Denny finds an expensive watch and gives it to his girlfriend, but it is soon revealed to be stolen merchandise. Troy Winbush as Denny. Alex Ruiz as Lou. Vanessa A. Williams as Jade.
第 25 集 Day of the Locusts
播出时间：1989年5月5日
Sondra comes down with strep throat, prompting her mother Clair and Elvin's mother Francine to "steal" the babies.
第 26 集 57 Varieties
播出时间：1989年5月12日
Theo wants to go to Egypt for an archaeological dig. Reno Wilson as Howard. Alex Ruiz as Lou. Deon Richmond as Kenny.
