第 5 季 共 10 集
播出时间：2020年12月29日
第 1 集 Leave it to the Nevus
播出时间：2020年12月29日
With pandemic safety protocols in place, Dr. Lee reopens her office. Monica has a large birthmark growing on the side of her face. Jackie has a melon-sized lump on the back of her shoulder. Reginald has large, rare growths on the back of his head.
第 2 集 Big Pop On Campus
播出时间：2021年1月5日
Dr. Lee tries to provide the help Reginald needs in order to remove two large rare growths on the back of his head; Che'Re has a prominent bump on her face that has put her in a dark place; and Juan has several painful boils on the back of his neck.
第 3 集 Cystic River
播出时间：2021年1月12日
Dennis has several giant growths on the back of his head. Juan has a rare condition he hopes Dr. Lee will understand. Natalie searches for answers as to why her body is covered in hundreds of mysterious dark bumps.
第 4 集 Don't Sweat It!
播出时间：2021年1月19日
Audrey pops the painful bumps that cover her body so she can feel relief. Felicia has a peculiar looking dark growth on her forehead. Krista's excessive sweating is so severe that on any given day she could fill up an entire milk jug with her sweat.
第 5 集 Pain the Neck
播出时间：2021年1月26日
John fears the large lump on his neck could become so big that it may eventually suffocate him. Shoshana is depressed because of the big growth on her forehead. Ashley hopes Dr. Lee can provide some relief from her three painful skin conditions.
第 6 集 Cyster, Cyster
播出时间：2021年2月2日
Yaellie, a sweet 9-year-old, has itchy psoriasis on over 90 percent of her body. Matt, a former Marine, has a large recurring lump in his armpit. Twins Tracie and Stacie have numerous matching bumps on their heads that sometimes leak.
第 7 集 Split Decision
播出时间：2021年2月9日
Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.
第 8 集 The Fault in Our Scars
播出时间：2021年2月16日
James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head.
第 9 集 Comedone Sail Away
播出时间：2021年2月23日
JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea.
第 10 集 A Spoonful of Cyst
播出时间：2021年3月2日
Stephen's large, bulbous nose gets him unwanted attention, and he hopes Dr. Lee can help; Veronica wants to be free of secrets, including the bump on her butt; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove himself.
