第 10 季 共 23 集
播出时间：2009年9月25日
第 1 集 Family Affair
播出时间：2009年9月25日
A rising young star is killed in a wreck and her determined stalker claims credit, but the team finds out there's more to this tragedy than meets the eye.
第 2 集 Ghost Town
播出时间：2009年10月2日
The son of a notorious killer is arrested on suspicion of murder, and the CSI team must overcome their natural prejudices against the boy's antecedents in order to track the true culprit.
第 3 集 Working Stiffs
播出时间：2009年10月9日
The team investigates the murder of Jason, a troubled computer geek working at a low-level casino support industry job who lures a colleague, Paulie, into a dangerous plan to make a working stiff's dream come true.
第 4 集 Coup de Grace
播出时间：2009年10月16日
When a policeman kills another officer, the CSIs must look to the evidence to determine if the shooting was premeditated or an accident.
第 5 集 Bloodsport
播出时间：2009年10月30日
After a beloved college football coach is found dead and his house drenched and spattered with his blood, the CSI team hunts for the killer who didn't find Coach Jimmy lovable at all.
第 6 集 Death and the Maiden
播出时间：2009年11月6日
When two seemingly different crimes turn out to be related, the CSIs discover they're interlocking parts of the same revenge plot.
第 7 集 The Lost Girls (III)
播出时间：2009年11月13日
(Crossover episode with CSI: Miami, Season 8 Episode 7 and CSI: New York, Season 6 Episode 7.)<br />
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In the third and final part of the CSI crossover, the CSI team helps Langston investigate a prostitution ring that may have harbored a hostage Langston has been looking for in Miami and New York.
第 8 集 Lover's Lanes
播出时间：2009年11月20日
A bowling tournament is disrupted when an important piece of evidence is uncovered, leading the CSIs to investigate a murder at the same bowling alley.
第 9 集 Appendicitement
播出时间：2009年12月11日
When Nick, Greg and Hodges take Henry to celebrate his birthday at a biker bar, they uncover a double homicide and find several suspects still at the bar who may be the murderers.
第 10 集 Better Off Dead
播出时间：2009年12月18日
The CSIs dig to find the truth about how a recent shootout at a gun store might connect to a young woman who may have committed suicide.
第 11 集 Sin City Blue
播出时间：2010年1月15日
Two secretaries on holiday from Arizona attempt to steal a man's wallet and ATM pin number in a scam, and wind up dead in different locations. Meanwhile, the CSI team also investigates a disturbing medical mystery involving the dumping of human organs in a wildlife refuge.
第 12 集 Long Ball
播出时间：2010年1月22日
The CSI investigates the mystifying death of a former pro golfer whose allegiance to the game might have cost him everything.
第 13 集 Internal Combustion
播出时间：2010年2月5日
The case of two high school students, one dead and one missing, lead the CSIs into the underbelly of streetcar racing and a tangled web of deadly competition.
第 14 集 Unshockable
播出时间：2010年3月5日
When a band member of Rascal Flatts is electrocuted by his own guitar during a concert, the CSI team investigates if it was a case of foul play.
第 15 集 Neverland
播出时间：2010年3月12日
When a young boy is found murdered, the CSI team uncovers evidence that may link his death to an old case that recently resurfaced.
第 16 集 The Panty Sniffer
播出时间：2010年4月2日
Catherine and Detective Vartann are thrown together in a hotel room for 24 hours as they stake out a duo making drugs in the room next door. Meanwhile, Nick and Langston work a case that involves a fetish which has become big business in Vegas.
第 17 集 Irradiator
播出时间：2010年4月9日
When the CSI team investigates the brutal murder of a family, they trace the killer to the house next door, which might belong to the "Dr. Jekyll" serial killer.
第 18 集 Field Mice
播出时间：2010年4月16日
When Hodges and Wendy take a group of high school CSI Explorer Scouts on a field trip, they embellish their role in solving cases and take their assignment a little bit too far.
第 19 集 World's End
播出时间：2010年4月23日
When a student is discovered murdered at Lindsey's school, the investigation takes a sharp turn when the CSIs uncover an unlikely connection between the boy's death and atrocities of the past.
第 20 集 Take My Life, Please!
播出时间：2010年4月30日
A legendary comic from the good old days of Las Vegas is set to reunite with his partner on stage for one night only, until one half of the famous duo is found dead.
第 21 集 Lost & Found
播出时间：2010年5月7日
A mother thought to be grieving for the loss of her family three years ago becomes a suspect in a CSI investigation.
第 22 集 Doctor Who
播出时间：2010年5月14日
The CSI team must investigate one of their own when Langston is accused by a former colleague of being part of the Dr. Jekyll murders, on part one of a two-part season finale of CSI.
第 23 集 Meat Jekyll
播出时间：2010年5月21日
The CSI's lives are on the line as they close in on the elusive Dr. Jekyll, and more than one member of the team may not live to see his capture, on part two of a two-part 10th season finale of CSI.
