第 4 季 共 24 集
播出时间：2006年9月19日
第 1 集 Working for Caligula
播出时间：2006年9月19日
Charlie returns to his bachelor lifestyle after Alan moves out of the house. Alan suffers a breakdown after his divorce from Kandi.
第 2 集 Who's Vod Kanockers?
播出时间：2006年9月26日
Charlie finally tells Alan that he didn't marry Mia because she wanted Alan and Jake to move out of the house, but Alan finds a hole in his logic. Charlie and Alan deal with a noisy neighbor who constantly sings all the time, who happens to be Steven Tyler.
第 3 集 The Sea Is a Harsh Mistress
播出时间：2006年10月3日
Charlie tries to surf to impress Dottie, a beautiful woman he just met, but after he nearly drowns he is convinced that he saw his late father.
第 4 集 A Pot Smoking Monkey
播出时间：2006年10月10日
Alan tries to hire his ex-wife's lawyer to help him win custody over the dog he and Kandi shared.
第 5 集 A Live Woman of Proven Fertility
播出时间：2006年10月17日
Alan is overjoyed by the prospect of Judith remarrying, as he would no longer have to pay alimony. Alan gets Charlie to help him when it looks like the marriage maybe derailed due to Jake’s dislike of his mother’s fiancé.
第 6 集 Apologies for the Frivolity
播出时间：2006年10月24日
Charlie is dating a woman whose personality and life are like his mother’s.
第 7 集 Repeated Blows to His Unformed Head
播出时间：2006年11月7日
Berta's daughter, Naomi is pregnant and Berta drags Charlie with her when she confronts the baby’s father. Alan reveals a secret fetish.
第 8 集 Release the Dogs
播出时间：2006年11月14日
Alan suffers from insomnia. He visits his psychiatrist (Jane Lynch), who reveals that the cause of Alan's sleepless nights is his jealousy towards Charlie, and his inability to glide through life.
第 9 集 Corey's Been Dead for an Hour
播出时间：2006年11月21日
Charlie gets tired of Alan's mooching and reaches the breaking point during the brothers' double date. Jake is left home alone for the first time.
第 10 集 Kissing Abraham Lincoln
播出时间：2006年11月28日
Worrying Charlie may get rid of one of them, Berta and Lydia fight over him. Meanwhile, Kandi does everything she can to stop Alan from selling their condo.
第 11 集 Walnuts and Demerol
播出时间：2006年12月12日
Charlie's friends and family put a crimp in his plan for a romantic Christmas Eve date. When Evelyn sees who the date is, she goes to great lengths to force a wedge between them.
第 12 集 Castrating Sheep in Montana
播出时间：2007年1月9日
Berta discovers that Alan has been dating her daughter Naomi.
第 13 集 Don't Worry, Speed Racer
播出时间：2007年1月23日
Jake shares that he has heard his mother having sex with her fiancée, Herb; this revelation brings up a repressed memory for Charlie. This leads Charlie to seek help from Rose.
第 14 集 That's Summer Sausage, Not Salami
播出时间：2007年2月6日
Charlie sets Alan up with their new neighbour. But he gets jealous when the two form a bond.
第 15 集 My Damn Stalker
播出时间：2007年2月13日
Rose is moving to London, and Charlie is surprised by his reaction to the news. Alan lies to a woman he met online.
第 16 集 Young People Have Phlegm Too
播出时间：2007年2月20日
Charlie's young, hot girlfriend takes him to a new club. She invites Alan to meet one of her friends but the men are shocked to learn that they are considered as being "old".
第 17 集 I Merely Slept With a Commie
播出时间：2007年2月27日
After Evelyn tells Alan and Charlie how she feels about there being no mourners at her friend’s funeral, the boys share their feelings that this could also be the case at her funeral. Evelyn tries to prove them wrong by introducing them to a couple she help adopt a boy from China. The boys return fire by inviting the young man to a play date with Jake.
第 18 集 It Never Rains in Hooterville
播出时间：2007年3月20日
Alan tries to bond with Jake when he realizes that his childhood is almost over. Kandi pursues a career in acting.
第 19 集 Smooth as a Ken Doll
播出时间：2007年4月10日
Charlie takes a liking to Myra, the witty sister of Judith's fiancé, Herb.
第 20 集 Aunt Myra Doesn't Pee a Lot
播出时间：2007年4月17日
Alan looks forward to Judith's wedding, while Charlie and Myra continue their romance.
第 21 集 Tucked, Taped and Gorgeous
播出时间：2007年4月24日
Alan and Charlie re-examine their sexual identities after Alan befriends Greg, a gay man. Meanwhile, Jake has a crush on Greg's daughter.
第 22 集 Mr. McGlue's Feedbag
播出时间：2007年5月1日
Jake gets lucky after Charlie takes him to the racetrack. Meanwhile, Alan has a difficult time at the DMV.
第 23 集 Anteaters. They're Just Crazy-Lookin'
播出时间：2007年5月8日
Charlie is shocked when the handyman working on his house beats him out for Chloe's affections. Alan has no sympathy for Charlie’s distress.
第 24 集 Prostitutes and Gelato
播出时间：2007年5月15日
Evelyn's boyfriend, Teddy, invites Alan and Charlie to go with him to Las Vegas on his private jet. The boys confront their individual 'daddy issues'
