第 3 季 共 24 集
播出时间：2000年7月29日
第 1 集 Fallen Arches
播出时间：2000年7月29日
Old super villain's break out of the retirement home, and the Powerpuff Girls get old super heroes out of retirement to beat them.
第 2 集 The Mane Event
播出时间：2000年7月29日
Bubbles and Buttercup do Blossom's hair, but when it gets tangled they give Blossom a bad hair day.
第 3 集 Town and Out
播出时间：2000年8月19日
The Professor gets a new job, and the Utonium family moves to the Town Of Citysville. The Professor loves it, but the girls' don't and are having a hard time to adjust to the new changes.
第 4 集 Child Fearing
播出时间：2000年8月19日
The Professor has to go out to an award's ceremony. He forgets to call the babysitter so he calls the Mayor who calls up Mojo Jojo to babysit.
第 5 集 Criss Cross Crisis
播出时间：2000年9月9日
The Professor gets a new job, and the Utonium family moves to the Town Of Citysville. The Professor loves it, but the girls' don't and are having a hard time to adjust to the new changes.
第 6 集 Bubblevision
播出时间：2000年9月16日
Bubbles has problems seeing, so she's forced to wear glasses.
第 7 集 Bought and Scold
播出时间：2000年9月16日
Princess buys Townsville and makes crime legal.
第 8 集 Gettin' Twiggy With It
播出时间：2000年9月23日
Ms. Keane assigns pet duty since its Friday. The Powerpuff Girls volunteer, but she chooses Mitch to take care of Twiggy, the class hamster.
第 9 集 Cop Out
播出时间：2000年9月23日
A lazy cop named Mike Bricoski lets his other fellow cops do the dirty work for him, but when he gets fired he takes his revenge out on the Powerpuff Girls.
第 10 集 Three Girls And A Monster
播出时间：2000年10月7日
Blossom and Buttercup have an argument thinking that brains or brawn is the best way to destroy a monster.
第 11 集 Monkey See, Doggy Two
播出时间：2000年10月7日
Mojo Jojo turns the world into dogs again. The Powerpuff Girls come to the rescue wondering why Mojo does the same plan again. He tells them that he's found a fatal flaw in his old plan as he watches a video of his old plan.
第 12 集 Jewel of the Aisle
播出时间：2000年10月21日
A dumb crook hides a jewel in a cereal box. He searches all 3000 of them and when he's down to his last one the Professor buys it for the girls'.
第 13 集 Super Zeroes
播出时间：2000年10月21日
After some inspiration from their favorite comics Blossom, Bubbles, and Buttercup try to become better heroes.
第 14 集 Candy Is Dandy
播出时间：2000年11月11日
When the Mayor rewards the Powerpuff Girls with candy for saving the day the girls' ask Mojo to commit more crimes, so they can get more candy.
第 15 集 Catastrophe
播出时间：2000年11月11日
An unbeatable slime monster comes to Townsville.
第 16 集 Hot Air Buffoon
播出时间：2000年12月2日
The Mayor gets sick and tired of the Powerpuff Girls saving the day so he decides to save the day by himself.
第 17 集 Ploys R' Us
播出时间：2000年12月2日
The Professor sleepwalks and steals toys at the same time. When the girls' find this out they have fun taking advantage of the situation.
第 18 集 The Headsucker's Moxy
播出时间：2001年1月6日
A new villain steals valuable information from smart people in Townsville, so the Powerpuff Girls use the Mayor as his new target.
第 19 集 Equal Fights
播出时间：2001年1月6日
A female villain named Femme Fatale teaches the girls' to be sexist, so she can get away with crimes.
第 20 集 Powerprof.
播出时间：2001年2月10日
The Professor tries to spend time with his daughters, but they fight crime to much. To solve the problem the Professor creates a power suit, so he could fight crime and spend time with the girls'.
第 21 集 Moral Decay
播出时间：2001年2月10日
After receiving a dollar from the Professor, Buttercup gets hooked and steals other people's teeth for the tooth fairy.
第 22 集 Meet the Beat Alls
播出时间：2001年2月10日
Mojo Jojo, Princess Morebucks, Fuzzy Lumpkins, and Him all team up as The Beat Alls to defeat the Powerpuff Girls. All is going well until Mojo Jojo falls in love with Moko Jono who breaks up the Beat Alls.
第 23 集 Helter Shelter
播出时间：2001年4月4日
Bubbles loves animals and the Professor is sick of her bringing them home, but when she brings home a baby whale the girls' try to hide him before the Professor comes home.
第 24 集 Power Lunch
播出时间：2001年4月4日
The Gang Green Gang raids a mini mart eating all types of foods. When the Powerpuff Girls arrive they use their heat vision which causes a chain reaction which gives the Gang Green Gang super powers.
